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2021-09-19 17:51
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Website：http://www.greenwaybiotek.com/ http://szgelinwei.xxhjjsj.com/
Beta arbutin
Solubility
In Vitro |
DMSO:≥50 mg/mL(183.65 mM) |
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|
Preparing Stock Solutions |
Concentration/Solvent/Mass |
1 mg |
5 mg |
10 mg |
|
1 mM |
3.6731ml |
18.3655ml |
36.7309ml |
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5 mM |
0.7346ml |
3.6731ml |
7.3462ml |
||
10 mM |
0.3673ml |
1.8365ml |
3.673ml |
||
Please refer to the solubility information to select the appropriate solvent. | |||||
1.Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80>> 45% saline | |||||
Description of Beta arbutin
Beta arbutin is an ideal whitening agent for whitening cosmetics, and the ß isomer with biological vitality. β-Arbutin is a white, slightly yellowish powder at room temperature. It is easily soluble in water, methanol, ethanol, propylene glycol, and glycerin aqueous solutions. After dissolution, there is no precipitation liquid, and it is insoluble in chloroform, ether, petroleum ether, etc. It is added in many whitening skin care products.
Product quality inspection report
Items |
Specifications |
Results |
Appearance |
White crystalline powder |
White crystalline |
Assay |
99.5%Min |
99.7% |
Melting point |
199~201±0.5℃ |
199-201 |
Clarity of water solution |
Transparency, colorless, none suspended matters |
Pass |
pH value of 1% aqueous |
5.0～7.0 |
6.17 |
Specific optical rotation |
【α】D20=-66±2º |
-65.8 |
Arsenic |
≤ 2 ppm |
pass |
Hydroquinone |
≤ 10 ppm |
pass |
Heavy metal |
≤ 10 ppm |
pass |
Loss on drying |
≤ 0.5% |
pass |
Ignition residue |
≤ 0.5% |
pass |
Pathogen |
Bacteria：≤ 300cfu/g |
< 20 |
Fungus：≤ 100cfu/g |
< 20 |
|
Conclusion |
Pass |
|
The mechanism of action of Beta arbutin
Beta arbutin (cas 497-76-7), also known as arbutin, refers to an active substance extracted from the leaves or fruits of bearberry. It is a white needle-shaped crystal or powder. It combines "green plants, safe and reliable" and " "Efficient depigmentation" is a skin depigmentation component that combines the three in one. It can quickly penetrate into the skin, while not affecting the cell proliferation concentration, it can effectively inhibit the activity of tyrosinase in the skin and block the formation of melanin. It directly binds with tyrosinase to accelerate the decomposition and excretion of melanin, thereby reducing skin pigmentation, removing stains and freckles, beta arbutin powder, and does not produce side effects such as toxicity, irritation, and sensitization to melanocytes. It has antiseptic and anti-inflammatory effects.
Beta arbutin USES
Beta arbutin is the safest and most effective whitening raw material that is popular today, and it is also the ideal skin whitening and anti-freckle active agent in the 21st century. Beta arbutin also has analgesic and anti-inflammatory effects. The main raw materials of common burns and scalds include arbutin. If it is applied to burns and scalds, it can reduce inflammation, reduce swelling, and speed up wound healing. Some products such as acne repair and other products The figure of arbutin is also commonly seen in.
Precautions for beta arbutin
1.Reardless of whether it is β-arbutin or α-arbutin, it can only be used externally, not orally. This point must be remembered to avoid adverse effects on the body.
2.When using beta arbutin, be careful to avoid sunlight. If used improperly, not only will it not inhibit melanin, but it will also cause the precipitation of melanin. So be careful when using it.
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